PROFILE


Tomotaka MURASHIGE

Tomotaka MURASHIGE, Ph.D

Postdoctoral Fellow of Japan Society for the Promotion of Science (JSPS)

■Laboratory

Okada-Hijikata Laboratory
Department of Mechanical Engineering, School of Engineering
Address: I6-325 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550 JAPAN
TEL: +81-3-5734-3840
FAX: +81-3-5734-3840
MAIL: murashige.t.aa[at]m.titech.ac.jp (Please change [at] to @)


■Personal profile

2004.4-2007.3 Yamanashi Gakuin Senior High School
2008.4-2012.3 Depertment of Mechanical Engineering, Tokyo University of Science
2012.4-2014.3 Graduate School of Schience and Technology, Tokyo University of Science
2014.4-2017.3 Graduate School of Schience and Technology, Tokyo University of Science (Maruyama LAB@AIST)
2014.4-2017.3 Research Fellow of Japan Society for the Promotion of Science (JSPS DC1)
2018.8-2019.6 Visiting Fellow, School of Engineering and Built Environment, Griffith University
2017.4-Present School of Engineering, Tokyo Institute of Technology (Okada-Hijikata LAB)
2017.4-Present Postdoctoral Fellow of Japan Society for the Promotion of Science (JSPS PD)


■Society

・Regular member, The Japan Society of Mechanical Engineering (JSME)
・Regular member, Japanese Society for Artificial Organs (JSAO)
・Associate member, Japanese Society for Medical and Biological Engineering (JSMBE)
・Regular member, The Society of Life Support Engineering (LSE)
・Regular member, The International Society for Mechanical Circulatory Support (ISMCS)
・y-ESAO member, European Society for Artificial Organs (ESAO)
・Regular member, The Institute of Electrical and Electronics Engineering (IEEE)
 (IEEE Engineering in Medical and Biology Society Membership)

RESEARCH


■Research on a centrifugal blood pump

・Investigation of a novel spiral groove geometiry for a blood pump.

・Evaluation of erythrocyte flow at a spiral groove bearing in a blood pump.

・Development of an intelligent artificial heart using a magnetic bearing.

ACHIEVEMENT


■Original Papers
  1. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O.
    "Feasibility of the optical imaging of thrombus formation in a rotary blood pump by near-infrared light" ,
    Artif Organs 2014;39(9):733-40.

  2. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Evaluation of a spiral groove geometiry for improvement of hemolysis level in a hydrodynamically levitated centrifugal blood pump" ,
    Artif Organs 2015;39(8):710-714.

  3. Sakota D, Murashige T, Kosaka R, Fujiwara T, Nishida M, Maruyama O.
    "Real-time observation of thrombus growth process in an impeller of a hydrodynamically levitated centrifugal blood pump by near-infrared hyperspectral imaging" ,
    Artif Organs 2015;39(8):714-719.

  4. Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Plasma skimming in a spiral groove bearing of a centrifugal blood pump" ,
    Artif Organs 2016;40(9):856-866.

  5. Sakota D, Murashige T, Kosaka R, Fujiwara T, Ouchi K, Nishida M, Maruyama O.
    "Noninvasive optical imaging of thrombus formation in mechanical circulatroy support devices" ,
    Journal of Biorheology 2016;30(1):6-12.

  6. Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Development of a method to calculate hematocrit in a bearing gap of a hydrodynamically levitated
    centrifugal blood pump (in Japanese)" ,
    Journal of Life Support Engineering 2017;29(2):42-48.

  7. Fujiwara T, Sakota D, Ouchi K, Endo S, Tahara T, Murashige T, Kosaka R, Oi K, Mizuno T, Maruyama O, Arai H.
    "Optical dynamic analysis of thrombus inside a centrifugal blood pump during extracorporeal mechanical
    circulatory support in a porcine model " ,
    Artificial Organs 2017;41(10):893-903.

  8. Murashige T, Hijikata W.
    "Mechanical antithrombogenic properties by vibrational excitation of the impeller in a magnetically levitated centrifugal blood pump",
    Artificial Organs 2019;43(9):849-859.

  9. Hijitaka W, Maruyama T, Murashige T, Sakota D, Maruyama O.
    "Detection of thrombosis in a magnetically levitated blood pump by vibrational excitation of the impeller",
    Artificial Organs:accepted

  10. Kawakami K, Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Maruyama O.
    "Reaction of human blood coagulation factors due to shear rate",
    Journal of Life Support Engineering:under review

  11. Inoue M, Ki KK, Murashige T, Simmonds MJ, Fraser JF, Watanabe N, Tansley GD, Chan CHH.
    "The effect of shear rate and exposure time on formation size of human platelet aggregation",
    Thrombosis Research:under review

■Conference Proceedings (with Peer Review)
  1. Murashige T, Kosaka R, Nishida M, Maruyama O, Yamane T, Kuwana K, Kawaguchi Y.
    "Fluid dynamic design for low hemolysis in a hydrodynamically levitated centrifugal blood pump",
    Conf Proc IEEE Eng Med Bio Soc 2013;2013:2732-5.

  2. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Evaluation of erythrocyte flow at a bearing gap in a hydrodynamically levitated centrifugal blood pump",
    Conf Proc IEEE Eng Med Bio Soc 2015;2015:270-273.

  3. Maruyama T, Murashige T, Sakota D, Maruyama O, Hijikata W.
    "Development of an intelligent ventricular assist device with a function of sensorless thrombus detection",
    Conf Proc IEEE Eng Med Bio Soc 2018;2018:4516-19.

  4. Jiang M, Murashige T, Sakota D, Hijikata W.
    "Evaluating plasma skimming with whole blood in small gap region imitating clearance of blood pump",
    Conf Proc IEEE Eng Med Bio Soc 2019;2019:5665-69.

■Presentations
  1. Murashige T, Kosaka R, Nishida M, Maruyama O, Yamane T, Kuwana K, Kawaguchi Y.
    "Fluid dynamic design for low hemolysis in a hydrodynamically levitated centrifugal blood pump",
    35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC),
    Osaka, 2013.7.4

  2. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Geometric design of the spiral groove in a hydrodynamically levitated centrifugal blood pump for improvement of the impeller levitation performance",
    21st Congress of the International Society for Rotary Blood Pumps (ISRBP),
    Yokohama, 2013.9.26

  3. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Geometric design of spiral groove bearing to reduce hemolysis in a hydrodynamically levitated centrifugal blood pump”,
    60th Annual Conference of American Society for Artificial Internal Organs (ASAIO),
    Washington D.C. (USA), 2014.6.20

  4. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "In vitro evaluation of the hemocompatibility in a hydrodynamically levitated centrifugal blood pump",
    22nd Congress of the International Society for Rotary Blood Pumps (ISRBP),
    San Francisco (USA), 2014.9.26

  5. Sakota D, Murashige T, Kosaka R, Nishida M, Maruyama O.
    "Hyperspectral imaging of thrombus growth process in a hydrodynamically levitated centrifugal blood pump",
    22nd Congress of the International Society for Rotary Blood Pumps (ISRBP),
    San Francisco (USA), 2014.9.26

  6. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Evaluation of erythrocyte flow at a bearing gap in a hydrodynamically levitated centrifugal blood pump",
    37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC),
    Milano (Italy), 2015.8.26

  7. Murashige T, Kosaka R, Sakota D, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Microscopic observation of erythrocyte behavior at a bearing gap in a hydrodynamically levitated centrifugal blood pump",
    23rd Annual Congress of the International Society for Rotary Blood Pumps (ISRBP),
    Dubrovnik (Croatia), 2015.9.27

  8. Fujiwara T, Sakota D, Ouchi K, Murashige T, Kosaka R, Nishida M, Endo S, Nagaoka E, Oi K,
    Mizuno T, Maruyama O, Arai H.
    "The real-time optical monitoring of thrombus formation inside the blood pump during extracorporeal circulation using hyperspectral imaging in acute animal experiments",
    23rd Annual Congress of the International Society for Rotary Blood Pumps (ISRBP),
    Dubrovnik (Croatia), 2015.9.28

  9. Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Effect of mean corpuscular volume on plasma skimming in a hydrodynamically levitated centrifugal blood pump",
    38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC),
    Orlando (USA), 2016.8.19

  10. Maruyama O, Kawakami K, Murashige T, Sakota D, Kosaka R, Nishida M, Yamane T.
    "In vitro quantitative thrombosis of bovine, porcine, and human blood under shear flow",
    24th Annual Congress of the International Society for Rotary Blood Pumps (ISRBP),
    Mito (Japan), 2016.9.21

  11. Murashige T, Sakota D, Kosaka R, Nishida M, Kawaguchi Y, Yamane T, Maruyama O.
    "Effect of animal species on plasma skimming in a hydrodynamic bearing of a centrifugal blood pump",
    24th Annual Congress of the International Society for Rotary Blood Pumps (ISRBP),
    Mito (Japan), 2016.9.22

  12. Kosaka R, Sakota D, Fujiwara T, Murashige T, Nishida M, Tahara T, Ouchi K, Arai H, Maruyama O.
    "Evaluation of hemocompatibility of a hydrodynamically levitated centrifugal blood pump using hyperspectral imaging in acute animal studies",
    44th Annual Congress of the European Society for Artificial Organs (ESAO),
    Vienna (Austria), 2017.9.8

  13. Maruyama O, Kawakami K, Murashige T, Sakota D, Kosaka R, Nishida M, Yamane T.
    "Shear-responsive blood coagulation factors related to inhibition of thrombosis",
    25th Annual Congress of the International Society of Mechanical Circulatory Support (ISMCS),
    Tucson (USA), 2017.10.16

  14. Maruyama T, Murashige T, Sakota D, Maruyama O, Hijikata W.
    "Sensorless detection of thrombus using real-time viscosity measurement in a magnetically-levitated rotary blood pump",
    25th Annual Congress of the International Society of Mechanical Circulatory Support (ISMCS),
    Tucson (USA), 2017.10.18

  15. Maruyama T, Murashige T, Sakota D, Maruyama O, Hijikata W.
    "Development of an intelligent ventricular assist device with a function of sensorless thrombus detection",
    40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC),
    Honolulu (USA), 2018.7.20

  16. Murashige T, Hijikata W.
    "Effect of impeller vibrational excitation on enhancing antithrombogenic properties of a centrifugal blood pump with a magnetic bearing",
    45th Annual Congress of the European Society for Artificial Organs (ESAO),
    Madrid (Spain), 2018.9.14

  17. Shoji K, Murashige T, Hijikata W.
    "Design of an axial blood pump with a large-gap passive levitation technology utilizing a combination of magnetic force and thrust force",
    26th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS),
    Odaiba (Japan), 2018.10.31

  18. Murashige T, Jiang M, Hijikata W.
    "Prevention of thrombus formation inside a magnetically levitated centrifugal blood pump using impeller vibrational excitation",
    26th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS),
    Odaiba (Japan), 2018.10.31

  19. Hijikata W, Murashige T, Maruyama T, Ogata A, Fujiwara T, Ohuchi K, Arai H.
    "Development of an intelligent blood pump with a self-detecting function of thrombus",
    26th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS),
    Odaiba (Japan), 2018.11.1

  20. Chan CHH, Igarashi K, Ki KK, Murashige T, Watanabe N, Simmonds MJ, Tansley G, Fraser JF.
    "Quantifying the effect of shear stress and exposure time induced total blood trauma using a novel blood-shear device",
    8th European Chapter of the Extracorporeal Life Support Organization (EuroELSO),
    Barcelona (Spain), 2019.4.12

  21. Chan CHH, Inoue M, Ki KK, Murashige T, Fraser JF, Simmonds MJ, Watanabe N, Tansley G.
    "The effect of shear rate and exposure time on the size of platelet aggregation",
    65th Annual Conference of American Society for Artificial Internal Organs (ASAIO),
    San Francisco (USA), 2019.6.29

  22. Jiang M, Murashige T, Sakota D, Hijikata W.
    "Evaluating plasma skimming with whole blood in small gap region imitating clearance of blood pump",
    41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC),
    Berlin (Germany), 2019.7.27

  23. Bieritz SA, Murashige T, Grande-Allen J, Tansley GD.
    "Visualizing red blood cell exclusion in a spiral groove bearing gap using erythrocyte ghosts and particle image velocimetry",
    27th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS)
    Bologna (Italy), 2019.10.21

  24. Inoue M, Ki KK, Murashige T, Simmonds MJ, Watanabe N, Fraser JF, Tansley GD, Chan CHH.
    "The effect of shear rate and exposure time on the formation size of human platelet aggregation",
    27th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS)
    Bologna (Italy), 2019.10.22

  25. Murashige T, Bieritz S, Chan CHH, Simmonds M, Tansley G.
    "Evaluation of hemolysis reduction by cell exclusion in a spiral groove hydrodynamic bearing",
    27th Annual Meeting of the International Society for Mechanical Circulatory Support (ISMCS)
    Bologna (Italy), 2019.10.21-23

  26. Murashige T, Maruyama O, Simmonds M, Tansley G, Chan CHH.
    "The effect of chosen assay, storage conditions and bilirubin concentrations on hemolysis level in multiple species",
    The 8th Meeting of the International Federation for Artificial Organs (IFAO)
    Osaka (Japan), 2019.11.14

  27. Seki H, Fujiwara T, Hijikata W, Ohuchi K, Murashige T, Maruyama T, Tahara T, Ogata A, Yokota S, Arai H.
    "Evaluation of thrombus detection methods in a magnetically levitated blood pump in an animal experiment",
    The 8th Meeting of the International Federation for Artificial Organs (IFAO)
    Osaka (Japan), 2019.11.14

  28. Seki H, Fujiwara T, Hijikata W, Ohuchi K, Murashige T, Maruyama T, Tahara T, Ogata A, Yokota S, Arai H.
    "Development of thrombus induction method at the target site using fibrinogen solution coating",
    The 8th Meeting of the International Federation for Artificial Organs (IFAO)
    Osaka (Japan), 2019.11.14

  29. Igarashi K, Murashige T, Katrina K, Simmonds M, Tansley G, Fraser J, Watanabe N, Chan CHH.
    "The threshold shear stress for mechanical damage as evaluated by hemolysis, red blood cell deformability and pletelet activation using a novel shearing device",
    The 8th Meeting of the International Federation for Artificial Organs (IFAO)
    Osaka (Japan), 2019.11.14

  30. Japasene conference: 15 presentations (First author), 28 presentations (Co-author).

■Awards
  1. "Research Encouragement Award",Human Technology Research Institute (AIST) (2014.6.12)
    Winner: Murashige T, et al.

  2. "Best Poster Award", Annual Meeting of the Japanese Society for Artificial Organs (2014.10.18)
    Winner: Murashige T, et al.

  3. "Conference President Award",Annual Meeting of the Japanese Society for Artificial Organs (2014.10.18)
    Winner: Murashige T, et al.

  4. "Young Scientist Award", Annual Meeting for Artificial heart and Assisted Circulation (2015.2.20)
    Winner: Murashige T, et al.

  5. "Helmut Reul Young Investigator Encouragement Award",
    Annual Congress of the International Society for Rotary Blood Pumps (2015.9.28)
    Winner: Murashige T, et al.

  6. "IEEE EMBC Japan Young Researcher Award (First Prize)",
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2015.11.1)
    Winner: Murashige T, et al.

  7. "Young Scientist Award (Basic research) (Third Prize)", Annual Meeting for Artificial heart and Assisted Circulation (2016.3.4)
    Winner: Murashige T, et al.

  8. "TUS Award", Tokyo University of Science (2017.3.16)
    Winner: Murashige T.

  9. "Young Scientist Award (Third Prize)", Annual Meeting for Artificial heart and Assisted Circulation (2018.2.9)
    Winner: Murashige T, et al.

  10. "IEEE EMBS Japan Chapter Young Researcher Award",
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society (2019.8.19)
    Winner: Jiang M, Murashige T, et al.

  11. "Helmut Reul Young Investigator Award",
    Annual Meeting of the International Society for Mechanical Circulatory Support (2019.10.22)
    Winner: Bieritz S, Murashige T, et al.

  12. "The Japan Society of Mechanical Engineering Young Scientist Best Presentation Award", LIFE2019 (2018.2.9)
    Winner: Inoue M, Murashige T, et al.

LINK


TOKYO INSTITUTE OF TECHNOLOGY
National Institute of Advanced Industrial Science and Technology (AIST)
Copy Right(C)2017 Tomotaka MURASHIGE All rights reserved.